Management of IgA nephropathy
ACE-inhibitors, ARBs and ACEI/ARB combinations - beneficial
Steroids
Pozzi et al (vs placebo) - better renal survival with steroids
Katafuchi et al (vs placebo) - similar renal survival
A recent metaanalysis also support use of steroids : reduce proteinuria, prevent progression to ESRD
Oral CYC
Ballardie et al. better 5-year renal survival
Fish Oil - conflicting results
Donadio et al. Mayo Clinic. NEJM 1994 (fish oil better)
Pettersson et al (no benefit, in fact worse)
Hogg et al (no benefit)
MMF - no evidence in IgAN
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2 comments:
Did you get this from the recent UpToDAte or elsewhere? Halim has a copy. Also I sent you all a 2007 on various primary GNs review, right? Datin
Yes, datin. I did. Thanks!
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